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Megaloblastic anemia - view of red blood cells
Megaloblastic anemia - view of red blood cells

Lack of intrinsic factor

Definition:

Intrinsic factor is a natural substance normally present in the stomach. It is essential to the digestion of vitamin B-12. Lack of intrinsic factor leads to pernicious anemia and vitamin B-12 deficiency.

Babies that are born without intrinsic factor cannot properly absorb vitamin B-12 starting around 6 months of age. The juvenile type of lack of intrinsic factor tends to manifest itself after the age of ten.



Alternative Names: Intrinsic factor - lack of

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Review Date: 2/4/2005
Reviewed By: Rita Nanda, M.D., Department of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.

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