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Digestive system organs
Digestive system organs

Drug-induced diarrhea

Definition:

Diarrhea can have many causes, including medications. Diarrhea is a common side effect of medications through a variety of mechanisms. For example:

  • Laxatives can produce diarrhea by drawing water into the gut, increasing the muscular contraction of the intestine, lubricating the lining of the gut, or a combination of these effects.
  • Antibiotics can produce diarrhea by destroying the normal bacteria of the intestine. These normal, good intestinal bacteria are called probiotics. Once these "friendly" bacteria are destroyed, a bad organism called Clostridium difficile may then colonize the GI tract. It can cause a severe, watery form of diarrhea called pseudomembranous colitis.
  • Other drugs may be directly toxic to the GI tract.
See the full article on diarrhea.

Alternative Names: Diarrhea associated with medications

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Prevention:

To prevent diarrhea related to antibiotic use, talk to your doctor about taking probiotic supplements. A commonly recommended amount is 1 to 2 billion viable cells of Lactobacillus acidophilus each day while you are taking antibiotics. Continue for a few days after the course of antibiotics is complete.




Review Date: 10/30/2004
Reviewed By: A.D.A.M. editorial.

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