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Herpetic esophagitis
Herpetic esophagitis
Upper gastrointestinal system
Upper gastrointestinal system

Herpes esophagitis

Definition:

Herpes esophagitis is an infection causing inflammation and ulcers in the esophagus. It is caused by the herpes simplex virus.



Causes, incidence, and risk factors:

Infection of the esophagus by the herpes simplex virus in individuals with normal immune systems is very rare and usually runs its course without treatment, but severe and persistent esophagitis can occur in an immunosuppressed or immunodeficient person.

Herpetic esophagitis causes excruciating pain when swallowing. The infection is frequently associated with fever and occasionally chills. Healthy individuals recover spontaneously in 3 to 5 days but those with weakened immune systems take longer.



Symptoms:

Signs and tests:
  • an EGD (esophagogastroduodenoscopy) with biopsy showing herpes
  • a culture of cells from esophageal brushings showing herpes
  • an esophagogastroduodenoscopy showing herpes lesions


Treatment:

The objective of treatment is to control the infection with antiviral medications, usually acyclovir. Pain medicine can also be given.



Support Groups:



Expectations (prognosis):

Esophagitis can usually be treated effectively. The outcome depends upon the underlying immunodeficiency that makes the person more susceptible to the infection.



Complications:

Complications include recurrent infections.



Calling your health care provider:

Call your health care provider if you have any condition that may result in reduced immune response and symptoms of esophagitis herpes develop.



Prevention:

The herpes simplex virus is contagious by direct contact, so avoid contact with known herpes lesions.




Review Date: 2/13/2006
Reviewed By: Monica Gandhi, M.D., M.P.H., Assistant Professor, Division of Infectious Diseases, UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network.

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