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Respiratory system
Respiratory system

Silicosis - acute

Definition:

Silicosis is a lung disease caused by inhaling silicon dioxide or crystalline silica dust without adequate protection. Acute silicosis is lung inflammation caused by intense exposure to silica over several months. Chronic silicosis, in contrast, is when lung scarring, nodules, and inflammation develop slowly from decades of exposure to silica dusts.



Alternative Names: Silicoproteinosis

Causes, incidence, and risk factors:

The disease occurs mainly in people who work in sandblasting, mining, quarrying, grinding, and those who work in foundries. Silicosis is becoming less common due to Occupational Safety and Health Administration (OSHA) regulations that require protective equipment.



Signs and tests:

The mucous membranes may have a bluish color (cyanosis). Often, the doctor can hear abnormal lung sounds with a stethoscope.

Possible tests include the following:

  • Chest x-ray that may show fluid-filled air spaces and thickening of lung tissue. Nodules are rarely seen (sometimes, an enlarged heart and dilated pulmonary arteries can be seen).
  • Pulmonary function tests
  • Arterial blood gases that show low concentration of oxygen
  • Chest CT scan
  • Lung biopsy
  • Bronchoscopy with bronchoalveolar lavage (BAL)
  • Sputum analysis


Treatment:

There is no specific treatment for silicosis. Whole-lung lavage or treatment with corticosteroids may be attempted. For those with end-stage lung disease, lung transplantation may be an option.

Supportive treatment includes cough suppression medications, bronchodilators, and oxygen if needed for shortness of breath. Antibiotics are prescribed for respiratory infections as needed. In general, silicosis patients should be screened for tuberculosis and treated if indicated.



Support Groups:



Expectations (prognosis):

The outcome is often rapidly progressive respiratory failure, possibly resulting in death.



Complications:

A complication is respiratory failure. Patients with silicosis are at increased risk of developing pulmonary tuberculosis.



Calling your health care provider:

Call for an appointment with your health care provider if you have an occupational exposure to silica and symptoms develop.



Prevention:

If you work in a high-risk occupation, wear a dust mask and do not smoke. Other protection such as respirators may be needed.




Review Date: 2/1/2005
Reviewed By: Allen J. Blaivas, D.O., Division of Pulmonary and Critical Care Medicine, UMDNJ-New Jersey Medical School, Newark, NJ. Review provided by VeriMed Healthcare Network.

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