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Health Information Encyclopedia - Poison


Amitriptyline hydrochloride overdose

Definition:

This is poisoning from taking an excessive amount of amitriptyline hydrochloride, a tricyclic antidepressant.



Alternative Names: Elavil overdose; Adepril overdose; Endep overdose; Enovil overdose; Trepiline overdose

Poisonous Ingredient:

Amitriptyline



Where Found:

Amitriptyline hydrochloride is a prescription medication. Brands include:

  • Adepril
  • Amitid
  • Amitril
  • Elavil
  • Emitrip
  • Endep
  • Enovil
  • Trepiline
  • Tryptanol
  • Vanatrip
Note: This list may not be all inclusive.

Symptoms:

Nervous system

Heart and blood

Lungs

Bladder and kidneys

Eyes, ears, nose, and throat

Gastrointestinal

  • Increased appetite
  • Constipation
  • Weight gain
  • Vomiting


Home Treatment:

This can be a very serious overdose. Seek immediate�medical help.



Before Calling Emergency:

Determine the following information:

  • Patient's age, weight, and condition
  • Name of the product (ingredients and strengths, if known)
  • Time it was swallowed
  • Amount swallowed
  • If the medication was prescribed for the patient


Poison Control, or a local emergency number:

The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the U.S. use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

Take the container with you to the hospital, if possible.

See National Poison Control center.



What to expect at the emergency room:

The health care provider will measure and monitor the patient's vital signs, including temperature, pulse, breathing rate, and blood pressure.

The patient may receive:

  • Fluids
  • Medicines to treat symptoms
  • Activated charcoal
  • Laxative
  • A nasogastric (NG) tube thru the nose into the stomach to empty the stomach (gastric lavage)���
  • Breathing help, possibly artificial respiration


Expectations (prognosis):

Amitriptyline hydrocholoride can be an extremely serious overdose.

Patients who swallow an excessive amount of this drug are almost always�admitted to hospital.

How well a patient does depends on how much of the drug was swallowed and how quickly treatment was received. The faster a patient gets medical help, the better the chance of recovery.




Review Date: 3/18/2006
Reviewed By: Janeen R. Azare, PhD, MSPH, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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